Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long sequence duplications, repeats, and palindromes in HIV-1 gp120: length variation in V4 as the product of misalignment mechanism.

Virology - 30 Mar 2010

Guglietta Silvia, Pantaleo Giuseppe, Graziosi Cecilia

Abstract excerpt

We have shown that indels in gp120 V4 are associated to the presence of duplicated and palindromic sequences, suggesting that they may be produced by strand-slippage misalignment mechanism. Indels in V4 involved region-specific duplications 9 to 15 bp long, and repeats of various lengths, associated to trinucleotides AAT. No duplications were found in V3 and C3. The frequency of palindromic sequences in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Frameshift Mutation
Share to Genes, env
Share to HIV Envelope Protein gp120

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Inverted Repeat Sequences

Share to Mutagenesis, Insertional

Share to Repetitive Sequences, Nucleic Acid

Share to Trinucleotide Repeats

Source

Identifiers

PMID: 20106497
DOI: 10.1016/j.virol.2009.12.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long sequence duplications, repeats, and palindromes in HIV-1 gp120: length variation in V4 as the product of misalignment mechanism.PMID 20106497Read ↗

Pause-melting misalignment: a novel model for the birth and motif indel of tandem repeats in the mitochondrial genome.Semantic proximity Read ↗

Efficient extension of a misaligned tRNA-primer during replication of the HIV-1 retrovirus.Semantic proximity Read ↗

Empirical and structural models for insertions and deletions in the divergent evolution of proteins.Semantic proximity Read ↗

The evolution of genome compression and genomic novelty in RNA viruses.Semantic proximity Read ↗

An abnormally long HIV-1 env DNA PCR product due to altered sequences of primer binding sites.Semantic proximity Read ↗

Inversions with deletions and duplications.Semantic proximity Read ↗

Role of the DIS hairpin in replication of human immunodeficiency virus type 1.Semantic proximity Read ↗

Incorporating information from length-mutational events into phylogenetic analysis.Semantic proximity Read ↗

Nonrandom distribution of cryptic repeating triplets of purines and pyrimidines (RNY)(n) in gp120 of HIV Type1.Semantic proximity Read ↗

In vitro evidence that UV-induced frameshift and substitution mutations at T tracts are the result of misalignment-mediated replication past a specific thymine dimer.Semantic proximity Read ↗

Opening of the TAR hairpin in the HIV-1 genome causes aberrant RNA dimerization and packaging.Semantic proximity Read ↗

Role of distal zinc finger of nucleocapsid protein in genomic RNA dimerization of human immunodeficiency virus type 1; no role for the palindrome crowning the R-U5 hairpin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.