Article
Functional telomere formation in yeast using synthetic C4A2 sequences.
Plasmid - 1 Jan 1990
Ascenzioni F, Guerrini A M, Donini P
Abstract excerpt
A yeast artificial chromosome (YAC) was constructed with a native autonomous replicating sequence (ARS) flanked telomere at one end and a 50-bp synthetic oligonucleotide of C4A2 repeats at the other. This was done in order to determine whether the presence of the flanking ARS sequence is required for telomere function. This construct was introduced into two different yeast strains: one mutated in the...
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