Article
Directional telomeric silencing and lack of canonical B1 elements in two silencer Autonomously Replicating Sequences in S. cerevisiae.
BMC molecular biology - 16 Nov 2012
Chisamore-Robert Patricia, Peeters Samantha, Shostak Kristina, Yankulov Krassimir
Abstract excerpt
BACKGROUND: Autonomously Replicating Sequences (ARS) in S. cerevisiae serve as origins of DNA replication or as components of cis-acting silencers, which impose positional repression at the mating type loci and at the telomeres. Both types of ARS can act as replicators or silencers, however it is not clear how these quite diverse functions are executed. It is believed that all ARS contain a core module of an...
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