Article
In vivo linearization and autonomous replication of plasmids containing human telomeric DNA in Aspergillus nidulans.
Molecular & general genetics : MGG - 1 Nov 1998
Aleksenko A, Ivanova L
Abstract excerpt
Plasmids containing two inverted 0.6-kb stretches of human telomeric repeats transform Aspergillus nidulans at frequencies characteristic of autonomously replicating vectors. Transformation frequency is not affected when the plasmids are linearized in vitro prior to transformation by cutting between the inverted repeats. Southern analysis reveals the presence of a homogeneous pool of linear plasmid molecules in...
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