In vivo linearization and autonomous replication of plasmids containing human telomeric DNA in Aspergillus nidulans.

doi:10.1007/s004380050881

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Article

In vivo linearization and autonomous replication of plasmids containing human telomeric DNA in Aspergillus nidulans.

Molecular & general genetics : MGG - 1 Nov 1998

Aleksenko A, Ivanova L

Abstract excerpt

Plasmids containing two inverted 0.6-kb stretches of human telomeric repeats transform Aspergillus nidulans at frequencies characteristic of autonomously replicating vectors. Transformation frequency is not affected when the plasmids are linearized in vitro prior to transformation by cutting betw...

Topics

Aspergillus nidulans
Blotting, Southern
DNA Replication
Genetic Engineering
Genetic Vectors
Humans
Mitosis
Mutation
Plasmids
Telomere
Transformation, Genetic

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