Article
Evolutionary dynamics of Candida albicans during in vitro evolution.
Eukaryotic cell - 1 Nov 2011
Huang Mian, McClellan Mark, Berman Judith, Kao Katy C
Abstract excerpt
While mechanisms of resistance to major antifungal agents have been characterized in Candida albicans, little is known about the evolutionary trajectories during the emergence of drug resistance. Here, we examined the evolutionary dynamics of C. albicans that evolved in vitro in the presence or absence of fluconazole using the visualizing evolution in real-time (VERT) method, a novel experimental approach that...
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