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Article

NAD(P)H oxidase p22(phox) polymorphism and cardiovascular function in amateur runners.

Acta physiologica (Oxford, England) - 1 Sept 2012

Gallina S, Di Francescomarino S, Di Mauro M, Izzicupo P, D'Angelo E, D'Amico M A, Pennelli A, Amicarelli F, Di Baldassarre A

Abstract excerpt

AIM: NAD(P)H system represents the major source of superoxide production at cardiovascular (CV) level. It has several genetic variants: in particular, the C242T polymorphism of its p22(phox) subunit is associated with a different oxidase activity, being the T allele related to a lower superoxide production. Although several authors investigated the protective effect of T allele in CV diseases, only few data are...

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Source

Identifiers

PMID: 22747689
DOI: 10.1111/j.1748-1716.2012.02456.x

Genes

CYBA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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NAD(P)H oxidase p22(phox) polymorphism and cardiovascular function in amateur runners.PMID 22747689Read ↗

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