Article
C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population.
Molecular biology reports - 1 Jan 2014
Hashad Ingy M, Abdel Rahman Mohamed F, Abdel-Maksoud Sahar M, Amr Khalda S, Effat Laila K, Shaban Gamal M, Gad Mohamed Z
Abstract excerpt
The p22phox protein subunit is essential for NADPH oxidase activity. The prevalence of C242T variants of p22phox gene was studied in 101 healthy Egyptian controls and 104 acute myocardial infarction (AMI) Egyptian patients. Contribution of oxidative stress, represented by serum oxidized-LDL (ox-LDL), in development of AMI was also examined and correlated with C242T gene variants. Genotyping and ox-LDL were...
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