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Article

BMP signals and the transcriptional repressor BLIMP1 during germline segregation in the mammalian embryo

31 Aug 2011

Abstract excerpt

Molecular factors and tissue compartments involved in the foundation of the mammalian germline have been mainly described in the mouse so far. To find mechanisms applicable to mammals in general, we analyzed temporal and spatial expression patterns of the transcriptional repressor BLIMP1 (also known as PRDM1) and the signaling molecules BMP2 and BMP4 in perigastrulation and early neurulation embryos of the rabbit...

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PMID: 21881976
DOI: 10.1007/s00427-011-0373-5

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