Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice.

Development (Cambridge, England) - 1 Dec 2007

Robertson Elizabeth J, Charatsi Iphigenie, Joyner Clive J, Koonce Chad H, Morgan Marc, Islam Ayesha, Paterson Carol, Lejsek Emily, Arnold Sebastian J, Kallies Axel, Nutt Stephen L, Bikoff Elizabeth K

Abstract excerpt

The zinc-finger transcriptional repressor Blimp1 (Prdm1) controls gene expression patterns during differentiation of B lymphocytes and regulates epigenetic changes required for specification of primordial germ cells. Blimp1 is dynamically expressed at diverse tissue sites in the developing mouse embryo, but its functional role remains unknown because Blimp1 mutant embryos arrest at E10.5 due to placental...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Branchial Region
Share to Embryonic Development

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryonic Stem Cells

Share to Fetal Heart

Share to Forelimb

Share to Multipotent Stem Cells

Share to Organ Specificity

Share to Positive Regulatory Domain I-Binding Factor 1

Source

Open in PubMed Open full text

Identifiers

PMID: 18039967
DOI: 10.1242/dev.012047
PMCID: PMC7116377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice.PMID 18039967Read ↗

Essential roles of a zebrafish prdm1/blimp1 homolog in embryo patterning and organogenesis.Semantic proximity Read ↗

Blimp1 is a critical determinant of the germ cell lineage in mice.Semantic proximity Read ↗

The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice.Semantic proximity Read ↗

Specification of the germ cell lineage in mice: A process orchestrated by the PR-domain proteins, Blimp1 and Prdm14Semantic proximity Read ↗

Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia.Semantic proximity Read ↗

BMP signals and the transcriptional repressor BLIMP1 during germline segregation in the mammalian embryoSemantic proximity Read ↗

The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells.Semantic proximity Read ↗

PRDM1/BLIMP1: a tumor suppressor gene in B and T cell lymphomasSemantic proximity Read ↗

Isl1Cre reveals a common Bmp pathway in heart and limb development.Semantic proximity Read ↗

Expression of the SMADIP1 gene during early human developmentSemantic proximity Read ↗

Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous GlandSemantic proximity Read ↗

Implantation and Gastrulation Abnormalities Characterize Early Embryonic Lethal Mouse LinesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.