Article
Essential roles of a zebrafish prdm1/blimp1 homolog in embryo patterning and organogenesis.
Development (Cambridge, England) - 1 Jan 2005
Wilm Thomas P, Solnica-Krezel Lilianna
Abstract excerpt
During vertebrate development the dorsal gastrula or Spemann-Mangold organizer orchestrates axis formation largely by limiting the ventralizing and posteriorizing activity of bone morphogenetic proteins (BMPs). In mouse and Xenopus laevis, genes encoding the zinc finger transcriptional repressor Prdm1/Blimp1 (PR domain containing 1, with ZNF domain; previously named B lymphocyte-induced maturation protein 1) were...
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