Article
Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus.
Genes and immunity - 1 Mar 2009
Fung E Y M G, Smyth D J, Howson J M M, Cooper J D, Walker N M, Stevens H, Wicker L S, Todd J A
Abstract excerpt
As a result of genome-wide association studies in larger sample sets, there has been an increase in identifying genes that influence susceptibility to individual immune-mediated diseases, as well as evidence that some genes are associated with more than one disease. In this study, we tested 17 single nucleotide polymorphisms (SNP) from 16 gene regions that have been reported in several autoimmune diseases...
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