Article
The type I diabetes association of the IL2RA locus.
Genes and immunity - 1 Dec 2009
Qu H-Q, Bradfield J P, Bélisle A, Grant S F A, Hakonarson H, Polychronakos C
Abstract excerpt
To confirm and fine map previous reports of association, the Type I Diabetes (T1D) Genetics Consortium (T1DGC) assembled a large collection of DNA samples from affected sib-pair (ASP) families with T1D (5003 affected individuals) and genotyped polymorphic markers. One of these loci, involving the IL2RA gene, had been reported to be due to three independent effects. The T1DGC genotyped 69 single-nucleotide...
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