Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Beta1-adrenergic receptor polymorphisms, QTc interval and occurrence of symptoms in type 1 of long QT syndrome.

International journal of cardiology - 31 May 2007

Paavonen Kristian J, Swan Heikki, Piippo Kirsi, Laitinen Päivi, Fodstad Heidi, Sarna Seppo, Toivonen Lauri, Kontula Kimmo, Viitasalo Matti

Abstract excerpt

BACKGROUND: The most prevalent LQT1 form of inherited long QT syndrome is caused by mutations of the KCNQ1 gene resulting repolarizing I(Ks) potassium current to decrease and the QT interval to prolong. As abrupt sympathetic activation triggers ventricular arrhythmias that may cause syncopal atta...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Electrocardiography
Share to Exercise Test
Share to Finland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to KCNQ1 Potassium Channel

Share to Long QT Syndrome

Share to Receptors, Adrenergic, beta-1

Share to Reference Values

Share to Regression Analysis

Source

Identifiers

PMID: 17023080
DOI: 10.1016/j.ijcard.2006.06.050

Genes

KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17023080-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Beta1-adrenergic receptor polymorphisms, QTc interval and occurrence of symptoms in type 1 of long QT syndrome.PMID 17023080Read ↗

Molecular pathogenesis of long QT syndrome type 1Semantic proximity Read ↗

Clinical aspects of the three major genetic forms of long QT syndrome (LQT1, LQT2, LQT3).Semantic proximity Read ↗

Genetic characterization of KCNQ1 variants improves risk stratification in type 1 long QT syndrome patients.Semantic proximity Read ↗

Long QT syndrome in adults.Semantic proximity Read ↗

Trigger-specific ion-channel mechanisms, risk factors, and response to therapy in type 1 long QT syndrome.Semantic proximity Read ↗

Clinical and molecular genetic risk determinants in adult long QT syndrome type 1 and 2 patients : Koponen et al. Follow-up of adult LQTS patients.Semantic proximity Read ↗

Age- and genotype-specific triggers for life-threatening arrhythmia in the genotyped long QT syndrome.Semantic proximity Read ↗

Modulating effects of age and gender on the clinical course of long QT syndrome by genotype.Semantic proximity Read ↗

Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers.Semantic proximity Read ↗

Gene-specific effect of beta-adrenergic blockade on corrected QT interval in the long QT syndrome.Semantic proximity Read ↗

Clinical Features, Long-Term Prognosis, and Clinical Management of Genotype-Negative Long QT Syndrome Patients.Semantic proximity Read ↗

Mutations in Conserved Amino Acids in the KCNQ1 Channel and Risk of Cardiac Events in Type‐1 Long‐QT SyndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.