Article
Clinical aspects of the three major genetic forms of long QT syndrome (LQT1, LQT2, LQT3).
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc - 1 May 2018
Kutyifa Valentina, Daimee Usama A, McNitt Scott, Polonsky Bronislava, Lowenstein Charles, Cutter Kris, Lopes Coeli, Zareba Wojciech, Moss Arthur J
Abstract excerpt
BACKGROUND: A comprehensive report on the clinical course of the three major genotypes of the long QT syndrome (LQTS) in a large U.S. patient cohort is lacking. METHODS: Our study consisted of 1,923 U.S. subjects from the Rochester-based LQTS Registry with genotype-positive LQT1 (n = 879), LQT2 (n = 807), and LQT3 (n = 237). We evaluated the risk of a first cardiac event (syncope, aborted cardiac arrest, or...
Topics
- Adolescent
- Adult
- Age Factors
- Child
- Child, Preschool
- Cohort Studies
- Electrocardiography
- Female
- Genotype
- Humans