Article
Unveiling specific triggers and precipitating factors for fatal cardiac events in inherited arrhythmia syndromes.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2015
Nakajima Tadashi, Kaneko Yoshiaki, Kurabayashi Masahiko
Abstract excerpt
Patients with inherited arrhythmia syndromes, such as long QT syndrome, Brugada syndrome, early repolarization syndrome, catecholaminergic polymorphic ventricular tachycardia, and their latent forms, are at risk for fatal arrhythmias. These diseases are typically associated with genetic mutations that perturb cardiac ionic currents. The analysis of cardiac events by genotype-phenotype correlation studies has...
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