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Article

Cytotoxic T-lymphocyte antigen-4 genetic variants and risk of Ewing's sarcoma.

Genetic testing and molecular biomarkers - 1 Jun 2013

Feng Dapeng, Yang Xinghai, Li Shufeng, Liu Tielong, Wu Zhipeng, Song Yuanlin, Wang Jian, Gao Wenwu, Huang Quan, Huang Wending, Zheng Wei, Xiao Jianru

Abstract excerpt

Despite the knowledge of many genetic alterations present in Ewing's sarcoma (ES), the complexity of this disease precludes placing its biology into a simple conceptual framework. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) can decrease T-cell activation and attenuate antitumor responses. Polymorphisms in the CTLA-4 gene have been shown to be associated with different diseases. Here, we investigated the association...

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Identifiers

PMID: 23480667
DOI: 10.1089/gtmb.2012.0488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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