Article
Complex formation, phosphorylation, and localization of protein kinase A of Schizosaccharomyces pombe upon glucose starvation.
Bioscience, biotechnology, and biochemistry - 1 Jan 2011
Gupta Dipali Rani, Paul Swapan Kumar, Oowatari Yasuo, Matsuo Yasuhiro, Kawamukai Makoto
Abstract excerpt
Nine sam mutants that undergo sexual differentiation without requiring starvation in Schizosaccharomyces pombe were previously isolated. In this study, we identified a nonsense mutation on the pka1 locus in the sam6 mutant. pka1 encodes a catalytic subunit of protein kinase A (PKA). Replacement and overexpression of pka1 suppressed the KCl sensitivity and hyper-mating phenotype of sam6, confirming that sam6 is an...
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