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Article

Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe.

Eukaryotic cell - 1 Jun 2004

Stiefel Jeffrey, Wang Lili, Kelly David A, Janoo Rozmin T K, Seitz Jeffrey, Whitehall Simon K, Hoffman Charles S

Abstract excerpt

Schizosaccharomyces pombe utilizes two opposing signaling pathways to sense and respond to its nutritional environment. Glucose detection triggers a cyclic AMP signal to activate protein kinase A (PKA), while glucose or nitrogen starvation activates the Spc1/Sty1 stress-activated protein kinase (SAPK). One process controlled by these pathways is fbp1+ transcription, which is glucose repressed. In this study, we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclic AMP-Dependent Protein Kinases

Share to Gene Expression Regulation, Fungal

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Source

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Identifiers

PMID: 15189983
DOI: 10.1128/EC.3.3.610-619.2004
PMCID: PMC420129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe.PMID 15189983Read ↗

Schizosaccharomyces pombe adenylate cyclase suppressor mutations suggest a role for cAMP phosphodiesterase regulation in feedback control of glucose/cAMP signaling.Semantic proximity Read ↗

Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway.Semantic proximity Read ↗

Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein alpha subunit encoded by gpa2 (git8).Semantic proximity Read ↗

Sck1 negatively regulates Gpa2-mediated glucose signaling in Schizosaccharomyces pombe.Semantic proximity Read ↗

Schizosaccharomyces pombe Hsp90/Git10 is required for glucose/cAMP signaling.Semantic proximity Read ↗

Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgtlp family, is required for glucose and cyclic AMP signaling, cell wall integrity, and septation.Semantic proximity Read ↗

Six git genes encode a glucose-induced adenylate cyclase activation pathway in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

cAMP-dependent protein kinase involves calcium tolerance through the regulation of Prz1 in Schizosaccharomyces pombe.Semantic proximity Read ↗

Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase.Semantic proximity Read ↗

Complex formation, phosphorylation, and localization of protein kinase A of Schizosaccharomyces pombe upon glucose starvation.Semantic proximity Read ↗

Mutations that are synthetically lethal with a gas1Delta allele cause defects in the cell wall of Saccharomyces cerevisiae.Semantic proximity Read ↗

Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle controlSemantic proximity Read ↗

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