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Article

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype.

Current biology : CB - 2 Nov 2000

Uren A G, Wong L, Pakusch M, Fowler K J, Burrows F J, Vaux D L, Choo K H

Abstract excerpt

BACKGROUND: Survivin is a mammalian protein that carries a motif typical of the inhibitor of apoptosis (IAP)proteins, first identified in baculoviruses. Although baculoviral IAP proteins regulate cell death, the yeast Survivin homolog Bir1 is involved in cell division. To determine the function o...

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Source

Identifiers

PMID: 11084331
DOI: 10.1016/s0960-9822(00)00769-7

Genes

INCENP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11084331-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype.PMID 11084331Read ↗

INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis.Semantic proximity Read ↗

Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis.Semantic proximity Read ↗

Control of apoptosis and mitotic spindle checkpoint by survivin.Semantic proximity Read ↗

Survivin: A Bifunctional Inhibitor of Apoptosis ProteinSemantic proximity Read ↗

Survivin mutant (Surv-DD70, 71AA) disrupts the interaction of Survivin with Aurora B and causes multinucleation in HeLa cells.Semantic proximity Read ↗

Survivin study: What is the next wave?Semantic proximity Read ↗

Localization, dynamics, and function of survivin revealed by expression of functional survivinDsRed fusion proteins in the living cell.Semantic proximity Read ↗

An IAP in Action: The Multiple Roles of Survivin in Differentiation, Immunity and MalignancySemantic proximity Read ↗

Role of Survivin in cytokinesis revealed by a separation-of-function allele.Semantic proximity Read ↗

BIRC5/Survivin is a novel ATG12–ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cellsSemantic proximity Read ↗

The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis.Semantic proximity Read ↗

Human survivin is a kinetochore-associated passenger protein.Semantic proximity Read ↗

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