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Article

A reassessment of methylcholanthrene transformation in the C3H10T1/2 cell culture system.

Carcinogenesis - 1 May 1990

Chen A C, Brankow D W, Herschman H R

Abstract excerpt

We previously demonstrated that four tumorigenic methylcholanthrene (MCA) transformed cell lines derived from C3H10T1/2 cells each contain a common G34----T nucleotide alteration in the c-Ki-ras gene. In contrast, a non-tumorigenic MCA transformant does not contain this mutation. We have now examined 75 newly isolated MCA transformants of C3H10T1/2 cells for their degree of morphological transformation, the...

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PMID: 2185902
DOI: 10.1093/carcin/11.5.817

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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