Timing of the steps in transformation of C3H 10T 1/2 cells by X-irradiation.

doi:10.1038/307085a0

Back to search

Article

Timing of the steps in transformation of C3H 10T 1/2 cells by X-irradiation.

Nature - 1 Jan 2000

Kennedy A R, Cairns J, Little J B

Abstract excerpt

Transformation of cells in culture by chemical carcinogens or X rays seems to require at least two steps. The initial step is a frequent event; for example, after transient exposure to either methylcholanthrene or X rays, almost every cell of established lines of mouse embryo fibroblasts proved c...

Topics

Animals
Cell Transformation, Neoplastic
Clone Cells
Mice
Mutation
Probability
Time Factors
X-Rays

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.