Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Specificity of Escherichia coli mutD and mutL mutator strains.

Gene - 1 Mar 1990

Wu T H, Clarke C H, Marinus M G

Abstract excerpt

The products of the mutD and mutL genes of Escherichia coli are involved in proofreading by DNA polymerase III and DNA adenine MTase (Dam)-dependent mismatch repair, respectively. We have used the plasmid-borne bacteriophage P22 mnt gene as a target to determine the types of mutations produced in mutL25 and mutD5 strains. Of 60 mutations identified from mutL25 cells, 52 were transition mutations and of these the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair
Share to Escherichia coli
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Bacterial

Share to Genes, Viral

Share to Mutation

Share to Plasmids

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 2185133
DOI: 10.1016/0378-1119(90)90488-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Specificity of Escherichia coli mutD and mutL mutator strains.PMID 2185133Read ↗

The interaction of the Escherichia coli mutD and mutT pathways in the prevention of A:T-->C:G transversions.Semantic proximity Read ↗

DNA methylation alters the pattern of spontaneous mutation in Escherichia coli cells (mutD) defective in DNA polymerase III proofreading.Semantic proximity Read ↗

A novel mutator of Escherichia coli carrying a defect in the dgt gene, encoding a dGTP triphosphohydrolase.Semantic proximity Read ↗

Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains.Semantic proximity Read ↗

Specificity of spontaneous mutations induced in mutA mutator cells.Semantic proximity Read ↗

mutA and mutC: two mutator loci in Escherichia coli that stimulate transversions.Semantic proximity Read ↗

The mutational specificity of two Escherichia coli dnaE antimutator alleles as determined from lacI mutation spectra.Semantic proximity Read ↗

Escherichia coli mutator (Delta)polA is defective in base mismatch correction: the nature of in vivo DNA replication errors.Semantic proximity Read ↗

Detection of DNA replication errors and 8-oxo-dGTP-mediated mutations in E. coli by Duplex DNA Sequencing.Semantic proximity Read ↗

The role of the mutT gene of Escherichia coli in maintaining replication fidelitySemantic proximity Read ↗

The Escherichia coli galK2 papillation assay: its specificity and application to seven newly isolated mutator strains.Semantic proximity Read ↗

The mutT defect does not elevate chromosomal fragmentation in Escherichia coli because of the surprisingly low levels of MutM/MutY-recognized DNA modifications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.