Article
Polymorphism of LRP5, but not of TNFRSF11B, is associated with a decrease in bone mineral density in postmenopausal Maya-Mestizo women.
American journal of human biology : the official journal of the Human Biology Council - 1 Jan 2000
Canto-Cetina Thelma, Polanco Reyes Lucila, González Herrera Lizbeth, Rojano-Mejía David, Coral-Vázquez Ramón Mauricio, Coronel Agustín, Canto Patricia
Abstract excerpt
OBJECTIVE: Osteoporosis is a complex disease characterized principally by low bone mineral density (BMD), which is determined by an interaction of genetic, metabolic, and environmental factors. The aim of this study was to analyze the possible association among one polymorphism of LRP5 and three polymorphisms of TNFRSF11B as well as their haplotypes with BMD variations in Maya-Mestizo postmenopausal women....
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