Coexpression of UmuD' with UmuC suppresses the UV mutagenesis deficiency of groE mutants.

doi:10.1128/jb.174.10.3133-3139.1992

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Article

Coexpression of UmuD' with UmuC suppresses the UV mutagenesis deficiency of groE mutants.

Journal of bacteriology - 1 May 1992

Donnelly C E, Walker G C

Abstract excerpt

The GroE proteins of Escherichia coli are heat shock proteins which have also been shown to be molecular chaperone proteins. Our previous work has shown that the GroE proteins of E. coli are required for UV mutagenesis. This process requires the umuDC genes which are regulated by the SOS regulon. As part of the UV mutagenesis pathway, the product of the umuD gene, UmuD, is posttranslationally cleaved to yield the...

Topics

Bacterial Proteins
Chaperonin 10
Chaperonin 60
Chaperonins
Cold Temperature
DNA-Directed DNA Polymerase
Escherichia coli
Escherichia coli Proteins
Gene Expression Regulation, Bacterial
Heat-Shock Proteins
Models, Biological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis

Mutation

Protein Processing, Post-Translational

SOS Response, Genetics

Suppression, Genetic

Ultraviolet Rays

Source

Open in PubMed Open full text

Identifiers

PMID: 1349601
DOI: 10.1128/jb.174.10.3133-3139.1992
PMCID: PMC205978

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1349601-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Coexpression of UmuD' with UmuC suppresses the UV mutagenesis deficiency of groE mutants.PMID 1349601Read ↗

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