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Article

Association of variations in TPH1 and HTR2B with gestational weight gain and measures of obesity.

Obesity (Silver Spring, Md.) - 1 Jan 2012

Kwak Soo Heon, Park Byoung Lae, Kim Hail, German Michael S, Go Min Jin, Jung Hye Seung, Koo Bo Kyong, Cho Young Min, Choi Sung Hee, Cho Yoon Shin, Shin Hyoung Doo, Jang Hak C, Park Kyong Soo

Abstract excerpt

Serotonin is involved in appetite regulation and energy homeostasis. Recently, it has been reported that 5-hydroxytryptamine receptor 2B (Htr2b) and tryptophan hydroxylase 1 (Tph1) play major role in β-cell proliferation in mouse during pregnancy. We investigated the genetic association of HTR2B and TPH1 with risk of gestational diabetes mellitus (GDM) and measures of obesity, in 869 Korean GDM women and...

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Source

Identifiers

PMID: 21836641
DOI: 10.1038/oby.2011.253

Genes

TPH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of variations in TPH1 and HTR2B with gestational weight gain and measures of obesity.PMID 21836641Read ↗

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