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Article

Further exploration of the possible influence of polymorphisms in HTR2C and 5HTT on body weight.

Metabolism: clinical and experimental - 1 Aug 2010

Bah Jessica, Westberg Lars, Baghaei Fariba, Henningsson Susanne, Rosmond Roland, Melke Jonas, Holm Göran, Eriksson Elias

Abstract excerpt

Receptors of the 5-HT2C subtype are of importance for the influence of serotonin on food intake, and 2 single nucleotide polymorphisms in this gene (HTR2C)--Cys23Ser (rs6318) and -759C>T (rs3813929)--have been reported to be associated with weight and/or antipsychotic-induced weight gain. The present study aimed to replicate these associations; in addition, the 5-HTTLPR polymorphism in the promoter region of the...

Topics

Adult
Body Mass Index
Body Weight
Female
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Polymorphism, Genetic

Promoter Regions, Genetic

Receptor, Serotonin, 5-HT2C

Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 20092861
DOI: 10.1016/j.metabol.2009.11.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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