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Article

Autoregulatory suppression of c-Myc by miR-185-3p.

The Journal of biological chemistry - 30 Sept 2011

Liao Jun-Ming, Lu Hua

Abstract excerpt

The expression of the c-myc oncogene at both protein and mRNA levels is transient and begins to be turned off 3-6 h after growth stimulation of cultured cells. The exact mechanism(s) underlying this down-regulation of c-Myc remains incompletely understood. Here we report the identification of miR-185-3p as a novel feedback regulator of c-Myc. This microRNA (miRNA) was initially identified as one of the c-Myc...

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Identifiers

PMID: 21832077
DOI: 10.1074/jbc.M111.262030
PMCID: PMC3190790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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