Article
The Myc Negative Autoregulation Mechanism Requires Myc-Max Association and Involves the c- myc P2 Minimal Promoter
1 Jan 1997
Abstract excerpt
Increasing evidence supports an important biological role for Myc in the downregulation of specific gene transcription. Recent studies suggest that c-Myc may suppress promoter activity through proteins of the basal transcription machinery. We have previously reported that Myc protein, in combination with additional cellular factors, suppresses transcription initiation from the c-myc promoter. To characterize the...
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