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Article

CRP gene variation affects early development of Alzheimer's disease-related plaques.

Journal of neuroinflammation - 11 Aug 2011

Kok Eloise Helena, Alanne-Kinnunen Mervi, Isotalo Karita, Luoto Teemu, Haikonen Satu, Goebeler Sirkka, Perola Markus, Hurme Mikko A, Haapasalo Hannu, Karhunen Pekka J

Abstract excerpt

INTRODUCTION: We used the Tampere Autopsy Study (TASTY) series (n = 603, age 0-97 yrs), representing an unselected population outside institutions, to investigate the pathogenic involvement of inflammation in Alzheimer's disease-related lesions. METHODS: We studied senile plaque (SP), neurofibrillary tangles (NFT) and SP phenotype associations with 6 reported haplotype tagging single nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21831326
DOI: 10.1186/1742-2094-8-96
PMCID: PMC3168418

Genes

CRP
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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