Article
Polymorphisms and haplotypes in the C-reactive protein gene and risk of dementia.
Neurobiology of aging - 1 Sept 2007
van Oijen Marieke, de Maat Moniek P M, Kardys Isabella, de Jong Frank Jan, Hofman Albert, Koudstaal Peter J, Witteman Jacqueline C, Breteler Monique M B
Abstract excerpt
OBJECTIVE: Inflammation plays a role in the pathogenesis of dementia and Alzheimer's disease (AD). Studies examining serum levels of C-reactive protein in relation to dementia yielded conflicting results. Since serum levels of C-reactive protein are partly determined by genetic factors, we examined the association between genetic variation in the C-reactive protein gene with dementia and AD. METHODS: This study...
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