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Genome‐wide association studies identify novel loci in rapidly progressive Alzheimer's disease

7 Jan 2024

Abstract excerpt

Abstract INTRODUCTION Recent data suggest that distinct prion‐like amyloid beta and tau strains are associated with rapidly progressive Alzheimer's disease (rpAD). The role of genetic factors in rpAD is largely unknown. METHODS Previously known AD risk loci were examined in rpAD cases. Genome‐wide association studies (GWAS) were performed to identify variants that influence rpAD. RESULTS We identified 115...

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PMID: 38184787
DOI: 10.1002/alz.13655

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