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Article

The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness

29 Aug 2017

Abstract excerpt

BACKGROUND: The Ghrelin-system is a complex, pleiotropic family composed of several peptides, including native-ghrelin and its In1-ghrelin splicing variant, and receptors (GHSR 1a/b), which are dysregulated in various endocrine-related tumors, where they associate to pathophysiological features, but the presence, functional role, and mechanisms of actions of In1-ghrelin splicing variant in prostate-cancer (PCa),...

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PMID: 28851363
DOI: 10.1186/s12943-017-0713-9

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