Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking.

doi:10.1176/appi.ajp.2011.10111579

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Article

Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking.

The American journal of psychiatry - 1 Oct 2011

Dong Li, Bilbao Ainhoa, Laucht Manfred, Henriksson Richard, Yakovleva Tatjana, Ridinger Monika, Desrivieres Sylvane, Clarke Toni-Kim, Lourdusamy Anbarasu, Smolka Michael N, Cichon Sven, Blomeyer Dorothea, Treutlein Jens, Perreau-Lenz Stephanie, Witt Stephanie, Leonardi-Essmann Fernando, Wodarz Norbert, Zill Peter, Soyka Michael, Albrecht Urs, Rietschel Marcella, Lathrop Mark, Bakalkin Georgy, Spanagel Rainer, Schumann Gunter

Abstract excerpt

OBJECTIVE: Circadian and stress-response systems mediate environmental changes that affect alcohol drinking. Psychosocial stress is an environmental risk factor for alcohol abuse. Circadian rhythm gene period 1 (Per1) is targeted by stress hormones and is transcriptionally activated in corticotropin releasing factor-expressing cells. The authors hypothesized that Per1 is involved in integrating stress response...

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Identifiers

PMID: 21828288
DOI: 10.1176/appi.ajp.2011.10111579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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