Article
Association of PER2 genotype and stressful life events with alcohol drinking in young adults.
PloS one - 1 Jan 2013
Blomeyer Dorothea, Buchmann Arlette F, Lascorz Jesus, Zimmermann Ulrich S, Esser Günter, Desrivieres Sylvane, Schmidt Martin H, Banaschewski Tobias, Schumann Gunter, Laucht Manfred
Abstract excerpt
BACKGROUND: Clock genes govern circadian rhythms and shape the effect of alcohol use on the physiological system. Exposure to severe negative life events is related to both heavy drinking and disturbed circadian rhythmicity. The aim of this study was 1) to extend previous findings suggesting an association of a haplotype tagging single nucleotide polymorphism of PER2 gene with drinking patterns, and 2) to examine...
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