Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerging targets in upper tract urothelial carcinomas: the TERT gene.

The Canadian journal of urology - 1 Dec 2022

Ortíz Restrepo Andrés, Ross Jeffrey S, Spiess Philippe E, Necchi Andrea, Li Roger, García-Perdomo Herney Andrés

Abstract excerpt

INTRODUCTION: Urothelial carcinoma (UC) is the fourth most prevalent malignancy in adults, accounting for 2.1% of cancer-related deaths. We aimed to describe the most frequent telomerase reverse transcriptase (TERT) gene mutations in this type of cancer and their relationship with the prognosis and treatment of this disease. MATERIALS AND METHODS: We performed a search strategy in Medline and Embase with the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Transitional Cell
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

Share to Telomerase

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 36495580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging targets in upper tract urothelial carcinomas: the TERT gene.PMID 36495580Read ↗

Effect of the TERT mutation on the prognosis of patients with urothelial carcinoma: a systematic review and meta-analysis.Semantic proximity Read ↗

Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis.Semantic proximity Read ↗

TERT promoter mutations and methylation for telomerase activation in urothelial carcinomas: New mechanistic insights and clinical significance.Semantic proximity Read ↗

Telomerase reverse transcriptase (TERT) promoter mutations are rare in urachal cancer.Semantic proximity Read ↗

Biological and clinical perspectives of TERT promoter mutation detection on bladder cancer diagnosis and management.Semantic proximity Read ↗

Implications of TERT promoter mutations and telomerase activity in solid tumors with a focus on genitourinary cancers.Semantic proximity Read ↗

Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancerSemantic proximity Read ↗

Recurrent TERT promoter mutations in urothelial carcinoma and potential clinical applications.Semantic proximity Read ↗

The association between the TERT rs2736100 AC genotype and reduced risk of upper tract urothelial carcinomas in a Han Chinese population.Semantic proximity Read ↗

TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCR.Semantic proximity Read ↗

<i>TERT</i> promoter mutations and telomerase reactivation in urothelial cancerSemantic proximity Read ↗

A hypothesis-generating analysis on the role of TERT promoter mutation in advanced urothelial carcinoma treated with immunotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.