Article
Topological maps of protein sequences.
Biological cybernetics - 1 Jan 1991
Ferrán E A, Ferrara P
Abstract excerpt
A new method based on neural networks to cluster proteins into families is described. The network is trained with the Kohonen unsupervised learning algorithm, using matrix pattern representations of the protein sequences as inputs. The components (x, y) of these 20 x 20 matrix patterns are the normalized frequencies of all pairs xy of amino acids in each sequence. We investigate the influence of different...
Topics
- Amino Acid Sequence
- Animals
- Humans
- Mathematics
- Molecular Sequence Data
- Mutation
- Neural Networks, Computer
- Proteins