Article
Antinuclear antibodies are associated with tumor necrosis factor receptor I gene polymorphism in patients with rheumatoid arthritis.
Clinical and experimental rheumatology - 1 Jan 2000
Glossop J R, Dawes P T, Mattey D L
Abstract excerpt
OBJECTIVES: Antinuclear antibodies (ANA) are a common feature of autoimmune diseases such as rheumatoid arthritis (RA). Herein, we investigate the relationship between ANA and polymorphism in the tumour necrosis factor receptor (TNFR) genes. METHODS: Serum titers of ANA at diagnosis were measured in 267 patients with RA and a single nucleotide polymorphism (SNP) in each of the TNFR-I (36A/G) and TNFR-II (676T/G)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
