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Article

Tumor necrosis factor receptor II gene polymorphism and severity of rheumatoid arthritis.

Arthritis and rheumatism - 1 Mar 2004

Constantin Arnaud, Dieudé Philippe, Lauwers-Cancès Valérie, Jamard Bénédicte, Mazières Bernard, Cambon-Thomsen Anne, Cornélis François, Cantagrel Alain

Abstract excerpt

OBJECTIVE: The gene encoding tumor necrosis factor receptor type II (TNFRII) is a strong candidate in the pathogenesis of rheumatoid arthritis (RA). An association between a single-nucleotide polymorphism (196M/R) in exon 6 of the TNFRII gene and familial RA was recently reported. The present study was undertaken to test the hypothesis that there is an association between this polymorphism and the severity of RA....

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PMID: 15022314
DOI: 10.1002/art.20113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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