Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carbohydrate Response Element Binding Protein Gene Expression Is Positively Regulated by Thyroid Hormone

26 Mar 2009

Abstract excerpt

The molecular mechanism of thyroid hormone (TH) effects to fatty acid metabolism in liver is yet to be clear. The carbohydrate response element-binding protein (ChREBP) as well as sterol response element-binding protein (SREBP)-1c plays a pivotal role in hepatic lipogenesis. Both SREBP-1c and ChREBP are target genes of liver X receptors (LXRs). Because LXRs and TH receptors (TRs) cross talk mutually in many...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to Steroid Chemistry and Biochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19324998
DOI: 10.1210/en.2009-0059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carbohydrate Response Element Binding Protein Gene Expression Is Positively Regulated by Thyroid HormonePMID 19324998Read ↗

Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene ExpressionSemantic proximity Read ↗

Liver X Receptor-α Gene Expression Is Positively Regulated by Thyroid HormoneSemantic proximity Read ↗

Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivoSemantic proximity Read ↗

Hepatic Elovl6 gene expression is regulated by the synergistic action of ChREBP and SREBP-1c.Semantic proximity Read ↗

Human SREBP1c expression in liver is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha).Semantic proximity Read ↗

The Insulin-like Growth Factor-binding Protein 1 Gene Is a Primary Target of Peroxisome Proliferator-activated ReceptorsSemantic proximity Read ↗

Effect of thyroid hormone on gene expressionSemantic proximity Read ↗

Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinomaSemantic proximity Read ↗

Human Spot 14 Glucose and Thyroid Hormone Response: Characterization and Thyroid Hormone Response Element IdentificationSemantic proximity Read ↗

Glucose-stimulated upregulation of GLUT2 gene is mediated by sterol response element-binding protein-1c in the hepatocytes.Semantic proximity Read ↗

SREBP-1 Interacts with Hepatocyte Nuclear Factor-4α and Interferes with PGC-1 Recruitment to Suppress Hepatic Gluconeogenic GenesSemantic proximity Read ↗

Estrogen stimulates SREBP2 expression in hepatic cell lines via an estrogen response element in the SREBP2 promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.