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Article

Coordination of TP53 abnormalities in breast cancer: data from analysis of TP53 polymorphisms, loss of heterozygosity, methylation, and mutations.

Genetic testing and molecular biomarkers - 1 Dec 2011

Denisov Evgeny V, Sukhanovskaya Tatiana V, Dultseva Tatiana S, Malinovskaya Elena A, Litviakov Nicolay V, Slonimskaya Elena M, Choinzonov Evgeny L, Cherdyntseva Nadezhda V

Abstract excerpt

AIMS: We have studied whether TP53 rs1042522, rs17878362, and rs1625895 alleles having a protective effect against breast cancer (BC) will be lost in tumors, whereas those allowing disease development will be retained. METHODS: Analysis of TP53 polymorphisms was performed in blood leukocytes and tumors from 80 Caucasian BC patients. In addition, TP53 loss of heterozygosity (LOH), methylation, and mutations were...

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Identifiers

PMID: 21810023
DOI: 10.1089/gtmb.2011.0038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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