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Article

Gender-stratified gene and gene-treatment interactions in smoking cessation.

The pharmacogenomics journal - 1 Dec 2012

Lee W, Bergen A W, Swan G E, Li D, Liu J, Thomas P, Tyndale R F, Benowitz N L, Lerman C, Conti D V

Abstract excerpt

We conducted gender-stratified analyses on a systems-based candidate gene study of 53 regions involved in nicotinic response and the brain-reward pathway in two randomized clinical trials of smoking cessation treatments (placebo, bupropion, transdermal and nasal spray nicotine replacement therapy). We adjusted P-values for multiple correlated tests, and used a Bonferroni-corrected α-level of 5 × 10(-4) to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 21808284
DOI: 10.1038/tpj.2011.30
PMCID: PMC3208134

Genes

CNR1
EPB41

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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