Article
Genetic variation in mu-opioid-receptor-interacting proteins and smoking cessation in a nicotine replacement therapy trial.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Nov 2007
Ray Riju, Jepson Christopher, Wileyto E Paul, Dahl John P, Patterson Freda, Rukstalis Margaret, Pinto Angela, Berrettini Wade, Lerman Caryn
Abstract excerpt
Extending a previous finding of an association between functional genetic variation in the mu-opioid receptor gene and response to nicotine replacement therapy, we explored the role of genetic variants in two genes encoding mu-opioid-receptor-interacting proteins, namely ARRB2 and HINT1. Participants were 374 smokers treated for nicotine dependence with either transdermal nicotine or nicotine nasal spray for 8...
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