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Article

The Role of A Priori-Identified Addiction and Smoking Gene Sets in Smoking Behaviors.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 16 Jul 2020

Evans Luke M, Johnson Emma C, Melroy-Greif Whitney E, Hewitt John K, Hoeffer Charles A, Keller Matthew C, Saba Laura M, Stitzel Jerry A, Ehringer Marissa A

Abstract excerpt

INTRODUCTION: Smoking is a leading cause of death, and genetic variation contributes to smoking behaviors. Identifying genes and sets of genes that contribute to risk for addiction is necessary to prioritize targets for functional characterization and for personalized medicine. METHODS: We performed a gene set-based association and heritable enrichment study of two addiction-related gene sets, those on the...

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Identifiers

PMID: 31930296
DOI: 10.1093/ntr/ntaa006
PMCID: PMC7749195

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