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Article

Pharmacogenetics of smoking cessation therapy

28 May 2009

Abstract excerpt

Nicotine dependence is a major health problem, with a large amount of smoking-related premature deaths and disabilities. The dependence mechanism of nicotine is especially complex and is under strong genetic influence. Smoking cessation is associated with substantial health benefits. Evidence from animal and human studies suggests that genetic polymorphisms influencing pharmacokinetics and pharmacodynamics of...

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PMID: 19475569
DOI: 10.1002/ajmg.b.30978

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