Article
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers.
The Cochrane database of systematic reviews - 8 Sept 2017
Schuit Ewoud, Panagiotou Orestis A, Munafò Marcus R, Bennett Derrick A, Bergen Andrew W, David Sean P
Abstract excerpt
BACKGROUND: Smoking cessation therapies are not effective for all smokers, and researchers are interested in identifying those subgroups of individuals (e.g. based on genotype) who respond best to specific treatments. OBJECTIVES: To assess whether quit rates vary by genetically informed biomarkers within pharmacotherapy treatment arms and as compared with placebo. To assess the effects of pharmacotherapies for...
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