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Article

Association between the 25129A > C polymorphism of the nuclear respiratory factor 2 gene and age-related macular degeneration.

Klinika oczna - 1 Jan 2013

Sliwiński Tomasz, Kołodziejska Urszula, Szaflik Jacek P, Błasiak Janusz, Szaflik Jerzy

Abstract excerpt

PURPOSE: Oxidative stress belongs to the main factors of pathogenesis of age-related macular degeneration, characterized by the damage to the retinal pigment epithelium cells and photoreceptors. Retinal pigment epithelium cells are rich in mitochondria, producing large amount of reactive oxygen species, which are by-products of the activity of the respiratory chain. The distribution in the activity of the chain...

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PMID: 24059022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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