Article
Association of complement factor H Y402H polymorphism with phenotype of neovascular age related macular degeneration in Israel.
Molecular vision - 1 Jan 2008
Chowers Itay, Cohen Yoram, Goldenberg-Cohen Nitza, Vicuna-Kojchen Joaquin, Lichtinger Alejandro, Weinstein Orly, Pollack Ayala, Axer-Siegel Ruth, Hemo Itzhak, Averbukh Edward, Banin Eyal, Meir Tal, Lederman Michal
Abstract excerpt
PURPOSE: The Tyr402His variant of complement factor H (CFH) is associated with age-related macular degeneration (AMD) in several populations. Our aim was to evaluate if this single nucleotide polymorphism (SNP) is associated with AMD in the Israeli population and see if it underlies heterogeneity in clinical manifestation and responses to photodynamic therapy (PDT), which characterize neovascular AMD (NVAMD)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.