Article
Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration.
Molecular vision - 10 Dec 2009
Fang Amy M, Lee Aaron Y, Kulkarni Mukti, Osborn Melissa P, Brantley Milam A
Abstract excerpt
PURPOSE: Genetic factors influence an individual's risk for developing neovascular age-related macular degeneration (AMD), a leading cause of irreversible blindness. Previous studies on the potential genetic link between AMD and vascular endothelial growth factor (VEGF), a key regulator of angiogenesis and vascular permeability, have yielded conflicting results. In the present case-control association study, we...
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