ARMS2/HTRA1 and CFH polymorphisms are not associated with choroidal neovascularization in highly myopic eyes of the elderly Japanese population.

doi:10.1038/eye.2009.215

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Article

ARMS2/HTRA1 and CFH polymorphisms are not associated with choroidal neovascularization in highly myopic eyes of the elderly Japanese population.

Eye (London, England) - 1 Jun 2010

Nakanishi H, Gotoh N, Yamada R, Yamashiro K, Otani A, Hayashi H, Tsujikawa A, Shimada N, Ohno-Matsui K, Mochizuki M, Saito M, Saito K, Iida T, Matsuda F, Yoshimura N

Abstract excerpt

PURPOSE: The purpose of this study was to investigate whether the genetic risk factors of age-related macular degeneration (AMD) are associated with the development of choroidal neovascularization (CNV) in highly myopic eyes of elderly Japanese. METHODS: Highly myopic elderly Japanese patients with and without CNV were genotyped for three AMD-associated single nucleotide polymorphisms (SNPs), namely rs10490924...

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Identifiers

PMID: 19680273
DOI: 10.1038/eye.2009.215

Genes

ARMS2
CFH
HTRA1

Variants

rs10490924

Provenance

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