Article
Usefulness of high clopidogrel maintenance dose according to CYP2C19 genotypes in clopidogrel low responders undergoing coronary stenting for non ST elevation acute coronary syndrome.
The American journal of cardiology - 15 Sept 2011
Cuisset Thomas, Quilici Jacques, Cohen William, Fourcade Laurent, Saut Noémie, Pankert Mathieu, Gaborit Bénédicte, Carrieri Patrizia, Morange Pierre-Emmanuel, Bonnet Jean Louis, Alessi Marie-Christine
Abstract excerpt
The cytochrome P450 (CYP) 2C19*2 loss-of-function allele has been associated with impaired clopidogrel response and worse prognosis in clopidogrel-treated patients. The benefit of tailored therapy according to platelet function test results remains unclear, and the potential effect of genotypes o...
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